 Bradykinin
"Bradykinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.
| Descriptor ID |
D001920
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| MeSH Number(s) |
D12.644.276.812.169 D12.644.400.090 D12.644.456.193 D12.776.467.812.169 D12.776.641.650.090 D23.469.050.375.110 D23.529.812.169
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| Concept/Terms |
Bradykinin- Bradykinin
- Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
- Arg Pro Pro Gly Phe Ser Pro Phe Arg
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Below are MeSH descriptors whose meaning is more general than "Bradykinin".
Below are MeSH descriptors whose meaning is more specific than "Bradykinin".
This graph shows the total number of publications written about "Bradykinin" by people in this website by year, and whether "Bradykinin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1991 | 0 | 2 | 2 | | 1992 | 3 | 0 | 3 | | 1993 | 2 | 0 | 2 | | 1994 | 2 | 2 | 4 | | 1995 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bradykinin" by people in Profiles.
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Alcock J, Warren AY, Goodson YJ, Hill SJ, Khan RN, Lymn JS. Inhibition of tissue transglutaminase 2 attenuates contractility of pregnant human myometrium. Biol Reprod. 2011 Apr; 84(4):646-53.
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Chen C, Lokhandwala MF. Potentiation by enalaprilat of fenoldopam-evoked natriuresis is due to blockade of intrarenal production of angiotensin-II in rats. Naunyn Schmiedebergs Arch Pharmacol. 1995 Aug; 352(2):194-200.
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Dickenson JM, Hill SJ. Selective potentiation of histamine H1-receptor stimulated calcium responses by 1,4-dithiothreitol in DDT1MF-2 cells. Biochem Pharmacol. 1994 Nov 01; 48(9):1721-8.
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Sakamoto T, Chen C, Lokhandwala MF. Contribution by bradykinin to the natriuretic response to the angiotensin converting enzyme inhibitor ramiprilat in spontaneously hypertensive rats. Naunyn Schmiedebergs Arch Pharmacol. 1994 Jul; 350(1):84-9.
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Marsh KA, Hill SJ. Des-Arg9-bradykinin-induced increases in intracellular calcium ion concentration in single bovine tracheal smooth muscle cells. Br J Pharmacol. 1994 Jul; 112(3):934-8.
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Dickenson JM, Bulmer S, Whittaker A, Salwey M, Hawley J, Hill SJ. Bradykinin B2- and 5-hydroxytryptamine (5-HT2)-receptor stimulated increases in intracellular calcium in cultured guinea-pig aortic smooth muscle cells. Biochem Pharmacol. 1994 Mar 15; 47(6):947-52.
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Marsh KA, Hill SJ. Characteristics of the bradykinin-induced changes in intracellular calcium ion concentration of single bovine tracheal smooth muscle cells. Br J Pharmacol. 1993 Sep; 110(1):29-35.
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Iredale PA, Martin KF, Hill SJ, Kendall DA. The effects of beta-phorbol-12,13 dibutyrate on agonist-induced increases in [Ca2+]i in N1E-115 cells. Differential modulation of responses to angiotensin II and bradykinin. Biochem Pharmacol. 1993 Feb 09; 45(3):611-7.
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Marsh KA, Hill SJ. Bradykinin B2 receptor-mediated phosphoinositide hydrolysis in bovine cultured tracheal smooth muscle cells. Br J Pharmacol. 1992 Oct; 107(2):443-7.
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Iredale PA, Martin KF, Hill SJ, Kendall DA. Agonist-induced changes in [Ca2+]i in N1E-115 cells: differential effects of bradykinin and carbachol. Eur J Pharmacol. 1992 Jun 05; 226(2):163-8.
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