Buprenorphine
"Buprenorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
| Descriptor ID |
D002047
|
| MeSH Number(s) |
D03.132.577.249.150 D03.549.686.150 D03.605.497.150 D04.615.723.795.150
|
| Concept/Terms |
Buprenex- Buprenex
- Reckitt & Colman Brand 1 of Buprenorphine Hydrochloride
Prefin- Prefin
- Key Brand of Buprenorphine Hydrochloride
Subutex- Subutex
- Essex Brand of Buprenorphine Hydrochloride
- Grünenthal Brand of Buprenorphine
- Buprenorphine Grünenthal Brand
- Grünenthal Brand of Buprenorphine Hydrochloride
- Temgésic
- Reckitt Benckiser Brand of Buprenorphine Hydrochloride
- Reckitt Brand of Buprenorphine Hydrochloride
- Schering-Plough Brand of Buprenorphine Hydrochloride
- Schering Plough Brand of Buprenorphine Hydrochloride
- Temgesic
- Buprex
- Reckitt & Colman Brand 2 of Buprenorphine Hydrochloride
6029-M- 6029-M
- 6029 M
- 6029M
- RX-6029-M
- RX 6029 M
- RX6029M
|
Below are MeSH descriptors whose meaning is more general than "Buprenorphine".
Below are MeSH descriptors whose meaning is more specific than "Buprenorphine".
This graph shows the total number of publications written about "Buprenorphine" by people in this website by year, and whether "Buprenorphine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 |
| 1991 | 1 | 0 | 1 |
| 1993 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Buprenorphine" by people in Profiles.
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Haile CN, Kosten TA, Kosten TR. Pharmacogenetic treatments for drug addiction: alcohol and opiates. Am J Drug Alcohol Abuse. 2008; 34(4):355-81.
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Rosenheck R, Kosten T. Buprenorphine for opiate addiction: potential economic impact. Drug Alcohol Depend. 2001 Aug 01; 63(3):253-62.
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Oliveto A, Kosten T, Schottenfeld R, Ziedonis D. Cocaine abuse among methadone-maintained patients. Am J Psychiatry. 1993 Nov; 150(11):1755.
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Kosten TA, Marby DW, Nestler EJ. Cocaine conditioned place preference is attenuated by chronic buprenorphine treatment. Life Sci. 1991; 49(24):PL201-6.
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Kosten TR, Morgan C, Kosten TA. Depressive symptoms during buprenorphine treatment of opioid abusers. J Subst Abuse Treat. 1990; 7(1):51-4.