 Naloxone
"Naloxone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
| Descriptor ID |
D009270
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| MeSH Number(s) |
D03.132.577.249.706 D03.549.686.750 D03.605.497.750 D04.615.723.795.706
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| Concept/Terms |
Nalone- Nalone
- SERB Brand of Naloxone Hydrochloride
Naloxon Curamed- Naloxon Curamed
- Curamed, Naloxon
- Curamed Brand of Naloxone Hydrochloride
Naloxon-ratiopharm- Naloxon-ratiopharm
- Naloxon ratiopharm
- Naloxonratiopharm
- ratiopharm Brand of Naloxone Hydrochloride
Naloxone Abello- Naloxone Abello
- Abello, Naloxone
- Abello Brand of Naloxone Hydrochloride
Narcan- Narcan
- Bristol-Myers Squibb Brand of Naloxone Hydrochloride
- Bristol Myers Squibb Brand of Naloxone Hydrochloride
- United Drug Brand of Naloxone Hydrochloride
- Lamepro Brand of Naloxone Hydrochloride
- Narcanti
- Boots Brand of Naloxone Hydrochloride
- Endo Brand of Naloxone Hydrochloride
MRZ-2593- MRZ-2593
- MRZ 2593
- MRZ2593
- MRZ 2593-Br
- MRZ 2593 Br
- MRZ 2593Br
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Below are MeSH descriptors whose meaning is more general than "Naloxone".
Below are MeSH descriptors whose meaning is more specific than "Naloxone".
This graph shows the total number of publications written about "Naloxone" by people in this website by year, and whether "Naloxone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1989 | 3 | 1 | 4 | | 1990 | 1 | 1 | 2 | | 1992 | 1 | 1 | 2 | | 1994 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Naloxone" by people in Profiles.
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Kosten TA, Bombace JC. Ethanol enhances naloxone sensitization and disrupts morphine discrimination--comparison to dizocilpine and pentobarbital: explanation of enhancing acute and attenuating chronic effects. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Aug; 25(6):1283-306.
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Wang NS, Stewart RB, Meisch RA. Orally delivered methadone as a reinforcer: Effects of the opioid antagonist naloxone. Drug Alcohol Depend. 1999 Jun 01; 55(1-2):79-84.
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Oliveto AH, Rosen MI, Kosten TA, Hameedi FA, Woods SW, Kosten TR. Hydromorphone-naloxone combinations in opioid-dependent humans under a naloxone novel-response discrimination procedure. Exp Clin Psychopharmacol. 1998 May; 6(2):169-78.
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Shoemaker WJ, Kosten TA, Muly SM. Ethanol attenuation of morphine dependence: comparison to dizocilpine. Psychopharmacology (Berl). 1997 Nov; 134(1):83-7.
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Kulkarni A, McVaugh W, Lawrence B, Pizzini R, Wolinsky I, VanBuren C, Rudolph F, Dafny N. Nutritional supplementation of nucleotides restores opioid CNS-mediated phenomena in mice. Life Sci. 1997; 61(17):1691-6.
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Kosten TA, DeCaprio JL, Rosen MI. The severity of naloxone-precipitated opiate withdrawal is attenuated by felbamate, a possible glycine antagonist. Neuropsychopharmacology. 1995 Dec; 13(4):323-33.
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Kosten TA. Clonidine attenuates conditioned aversion produced by naloxone-precipitated opiate withdrawal. Eur J Pharmacol. 1994 Mar 11; 254(1-2):59-63.
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Klitenick MA, DeWitte P, Kalivas PW. Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. J Neurosci. 1992 Jul; 12(7):2623-32.
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Alkadhi KA, Hogan YH. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission. J Auton Pharmacol. 1992 Feb; 12(1):15-23.
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Chintala MS, Jandhyala BS. Comparative evaluation of the effects of felodipine, hydralazine, and naloxone on the survival rate in rats subjected to a "fixed volume" model of hemorrhagic shock. Circ Shock. 1990 Nov; 32(3):219-29.
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