 Spermine
"Spermine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
| Descriptor ID |
D013096
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| MeSH Number(s) |
D02.092.211.415.701.801.821 D02.092.782.802
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermine".
Below are MeSH descriptors whose meaning is more specific than "Spermine".
This graph shows the total number of publications written about "Spermine" by people in this website by year, and whether "Spermine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spermine" by people in Profiles.
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DeWalt BW, Murphy JC, Fox GE, Willson RC. Compaction agent clarification of microbial lysates. Protein Expr Purif. 2003 Apr; 28(2):220-3.
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O'Shaughnessy JA, Demers LM, Jones SE, Arseneau J, Khandelwal P, George T, Gersh R, Mauger D, Manni A. Alpha-difluoromethylornithine as treatment for metastatic breast cancer patients. Clin Cancer Res. 1999 Nov; 5(11):3438-44.
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Alexander SP, Kendall DA, Hill SJ. Excitatory amino acid-induced phosphoinositide turnover in guinea pig cerebral cortical slices: selective enhancement by spermine of the response to DL-1-aminocyclopentane-trans-1,3-dicarboxylate. J Neurochem. 1992 Aug; 59(2):610-5.
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Alexander SP, Kendall DA, Hill SJ. Spermine enhances calcium- and GTP analogue-stimulated particulate phosphoinositidase. Biochem Soc Trans. 1992 Feb; 20(1):20S.
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Restivo KM, Drayer DE, Orto L, Bond O, Reidenberg MM. Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients. J Lab Clin Med. 1987 Aug; 110(2):217-20.
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