 Trypsin
"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 3 | 4 | | 2007 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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Mitchell M, Mali S, King CC, Bark SJ. Enhancing MALDI time-of-flight mass spectrometer performance through spectrum averaging. PLoS One. 2015; 10(3):e0120932.
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Donato GM, Goldsmith CS, Paddock CD, Eby JC, Gray MC, Hewlett EL. Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles. FEBS Lett. 2012 Feb 17; 586(4):459-65.
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Oldham JT, Hincapie M, Rejtar T, Wall PK, Carlson JE, Lee-Parsons CW. Shotgun proteomic analysis of yeast-elicited California poppy (Eschscholzia californica) suspension cultures producing enhanced levels of benzophenanthridine alkaloids. J Proteome Res. 2010 Sep 03; 9(9):4337-45.
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Bark SJ, Hook V. Differential recovery of peptides from sample tubes and the reproducibility of quantitative proteomic data. J Proteome Res. 2007 Nov; 6(11):4511-6.
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Bernhard OK, Kapp EA, Simpson RJ. Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. J Proteome Res. 2007 Mar; 6(3):987-95.
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Nam HW, Simpson R, Kim YS. N-terminal isotope tagging with propionic anhydride: proteomic analysis of myogenic differentiation of C2C12 cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 05; 826(1-2):91-107.
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Moritz RL, Clippingdale AB, Kapp EA, Eddes JS, Ji H, Gilbert S, Connolly LM, Simpson RJ. Application of 2-D free-flow electrophoresis/RP-HPLC for proteomic analysis of human plasma depleted of multi high-abundance proteins. Proteomics. 2005 Aug; 5(13):3402-13.
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Kapp EA, Schütz F, Connolly LM, Chakel JA, Meza JE, Miller CA, Fenyo D, Eng JK, Adkins JN, Omenn GS, Simpson RJ. An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: sensitivity and specificity analysis. Proteomics. 2005 Aug; 5(13):3475-90.
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Myatt A, Hill SJ. Trypsin stimulates the phosphorylation of p42,44 mitogen-activated protein kinases via the proteinase-activated receptor-2 and protein kinase C epsilon in human cultured prostate stromal cells. Prostate. 2005 Jul 01; 64(2):175-85.
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Moritz RL, Ji H, Schütz F, Connolly LM, Kapp EA, Speed TP, Simpson RJ. A proteome strategy for fractionating proteins and peptides using continuous free-flow electrophoresis coupled off-line to reversed-phase high-performance liquid chromatography. Anal Chem. 2004 Aug 15; 76(16):4811-24.
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