DNA Probes
"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
Descriptor ID |
D015342
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MeSH Number(s) |
D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
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Concept/Terms |
DNA Probes- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
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Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
This graph shows the total number of publications written about "DNA Probes" by people in this website by year, and whether "DNA Probes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1988 | 0 | 1 | 1 | 1990 | 1 | 1 | 2 | 1991 | 0 | 1 | 1 | 1992 | 0 | 1 | 1 | 1993 | 0 | 1 | 1 | 1994 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 0 | 3 | 3 | 1998 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 0 | 2 | 2 | 2006 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
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Patel SN, Wu Y, Bao Y, Mancebo R, Au-Young J, Grigorenko E. TaqMan® OpenArray® high-throughput transcriptional analysis of human embryonic and induced pluripotent stem cells. Methods Mol Biol. 2013; 997:191-201.
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Putonti C, Chumakov S, Mitra R, Fox GE, Willson RC, Fofanov Y. Human-blind probes and primers for dengue virus identification. FEBS J. 2006 Jan; 273(2):398-408.
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Kourentzi KD, Fox GE, Willson RC. Hybridization-responsive fluorescent DNA probes containing the adenine analog 2-aminopurine. Anal Biochem. 2003 Nov 01; 322(1):124-6.
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Davis FJ, Gupta M, Camoretti-Mercado B, Schwartz RJ, Gupta MP. Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy. J Biol Chem. 2003 May 30; 278(22):20047-58.
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Kourentzi KD, Fox GE, Willson RC. Microbial identification by immunohybridization assay of artificial RNA labels. J Microbiol Methods. 2002 May; 49(3):301-6.
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Criswell DS, Booth FW, DeMayo F, Schwartz RJ, Gordon SE, Fiorotto ML. Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. Am J Physiol. 1998 Sep; 275(3 Pt 1):E373-9.
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Grigorenko E, Glazier S, Bell W, Tytell M, Nosel E, Pons T, Deadwyler SA. Changes in glutamate receptor subunit composition in hippocampus and cortex in patients with refractory epilepsy. J Neurol Sci. 1997 Dec 09; 153(1):35-45.
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Quiambao AB, Peachey NS, Mangini NJ, Röhlich P, Hollyfield JG, al-Ubaidi MR. A 221-bp fragment of the mouse opsin promoter directs expression specifically to the rod photoreceptors of transgenic mice. Vis Neurosci. 1997 Jul-Aug; 14(4):617-25.
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Freeman MR, Yoo JJ, Raab G, Soker S, Adam RM, Schneck FX, Renshaw AA, Klagsbrun M, Atala A. Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder. J Clin Invest. 1997 Mar 01; 99(5):1028-36.
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Yang Y, Fox GE. An Archaea 5S rRNA analog is stably expressed in Escherichia coli. Gene. 1996 Feb 02; 168(1):81-5.
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