4-Aminopyridine
"4-Aminopyridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the POTASSIUM CHANNEL BLOCKERS, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel subtypes.
| Descriptor ID |
D015761
|
| MeSH Number(s) |
D02.092.080.060 D03.383.725.050.060
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "4-Aminopyridine".
Below are MeSH descriptors whose meaning is more specific than "4-Aminopyridine".
This graph shows the total number of publications written about "4-Aminopyridine" by people in this website by year, and whether "4-Aminopyridine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 |
| 1984 | 0 | 1 | 1 |
| 1989 | 0 | 1 | 1 |
| 1991 | 0 | 1 | 1 |
| 1993 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Aminopyridine" by people in Profiles.
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Alkadhi KA. Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia. Clin Exp Hypertens. 2008 Oct; 30(7):497-510.
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Liu B, Arulkumaran S, Hill SJ, Khan RN. Comparison of potassium currents in human decidua before and after the onset of labor. Biol Reprod. 2003 Jun; 68(6):2281-8.
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Wisgirda ME, Dryer SE. Characteristics of multiple voltage-activated K+ currents in acutely dissociated chick ciliary ganglion neurones. J Physiol. 1993 Oct; 470:171-89.
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Dryer SE, Dourado MM, Wisgirda ME. Properties of Ca2+ currents in acutely dissociated neurons of the chick ciliary ganglion: inhibition by somatostatin-14 and somatostatin-28. Neuroscience. 1991; 44(3):663-72.
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Alkadhi KA, Hogan YH. Effect of calcium on synaptic facilitation by potassium channel blockers in superior cervical ganglion of rat. Neuropharmacology. 1989 Jan; 28(1):75-81.
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Alkadhi KA, Brown TR, Sabouni MH. Inhibitory effect of adenosine on transmission in sympathetic ganglia. Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov; 328(1):16-9.
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Volle RL, Quenzer LF, Patterson BA, Alkadhi KA, Henderson EG. Cyclic guanosine 3':5'-monophosphate accumulation and 45Ca-uptake by rat superior cervical ganglia during preganglionic stimulation. J Pharmacol Exp Ther. 1981 Nov; 219(2):338-43.