 Pyrilamine
"Pyrilamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
| Descriptor ID |
D011738
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| MeSH Number(s) |
D03.383.725.050.805
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| Concept/Terms |
Mepyramine Maleate- Mepyramine Maleate
- Maleate, Mepyramine
- Pyrilamine Maleate
- Maleate, Pyrilamine
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Below are MeSH descriptors whose meaning is more general than "Pyrilamine".
Below are MeSH descriptors whose meaning is more specific than "Pyrilamine".
This graph shows the total number of publications written about "Pyrilamine" by people in this website by year, and whether "Pyrilamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1981 | 3 | 0 | 3 | | 1982 | 0 | 1 | 1 | | 1983 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 2 | 2 | | 1987 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 2 | 2 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 1 | 2 | 3 | | 1996 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrilamine" by people in Profiles.
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Rose RH, Briddon SJ, Hill SJ. A novel fluorescent histamine H(1) receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands. Br J Pharmacol. 2012 Mar; 165(6):1789-1800.
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Nammi S, Gudavalli R, Babu BS, Lodagala DS, Boini KM. Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs. BMC Complement Altern Med. 2003 Oct 16; 3:5.
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Clark EA, Hill SJ. Sensitivity of histamine H3 receptor agonist-stimulated [35S]GTP gamma[S] binding to pertussis toxin. Eur J Pharmacol. 1996 Jan 25; 296(2):223-5.
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Peakman MC, Hill SJ. Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. Br J Pharmacol. 1994 Dec; 113(4):1554-60.
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Dickenson JM, Hill SJ. Selective potentiation of histamine H1-receptor stimulated calcium responses by 1,4-dithiothreitol in DDT1MF-2 cells. Biochem Pharmacol. 1994 Nov 01; 48(9):1721-8.
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Dickenson JM, Hill SJ. Characteristics of [3H]mepyramine binding in DDT1MF-2 cells: evidence for high affinity binding to a functional histamine H1 receptor. Eur J Pharmacol. 1994 Jul 15; 268(2):257-62.
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Iredale PA, Fukui H, Hill SJ. High, stable expression of the bovine histamine H1-receptor coupled to [Ca2+]i mobilisation in CHO-K1 cells. Biochem Biophys Res Commun. 1993 Sep 30; 195(3):1294-300.
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Dickenson JM, Hill SJ. Histamine H1-receptor-mediated calcium influx in DDT1MF-2 cells. Biochem J. 1992 Jun 01; 284 ( Pt 2):425-31.
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Dickenson JM, Hill SJ. Histamine-stimulated increases in intracellular calcium in the smooth muscle cell line, DDT1MF-2. Biochem Pharmacol. 1991 Sep 27; 42(8):1545-50.
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Iredale PA, Ruck A, Martin KF, Kendall DA, Hill SJ. Histamine-induced changes in intracellular calcium in undifferentiated N1E-115 cells. Biochem Soc Trans. 1991 Feb; 19(1):6S.
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