Mutagenesis, Insertional
"Mutagenesis, Insertional" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Descriptor ID |
D016254
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MeSH Number(s) |
E05.393.420.601.550 G05.355.600.550 G05.365.590.575
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Concept/Terms |
Sequence Insertion- Sequence Insertion
- Insertion, Sequence
- Insertions, Sequence
- Sequence Insertions
Gene Insertion- Gene Insertion
- Gene Insertions
- Insertion, Gene
- Insertions, Gene
Insertion Mutation- Insertion Mutation
- Insertion Mutations
- Mutation, Insertion
- Mutations, Insertion
Insertional Activation- Insertional Activation
- Activation, Insertional
- Activations, Insertional
- Insertional Activations
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Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Insertional".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Insertional".
This graph shows the total number of publications written about "Mutagenesis, Insertional" by people in this website by year, and whether "Mutagenesis, Insertional" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1991 | 0 | 1 | 1 | 1994 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1999 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mutagenesis, Insertional" by people in Profiles.
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Yergeau DA, Kelley CM, Kuliyev E, Zhu H, Sater AK, Wells DE, Mead PE. Remobilization of Tol2 transposons in Xenopus tropicalis. BMC Dev Biol. 2010 Jan 22; 10:11.
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Hirunsatit R, George ED, Lipska BK, Elwafi HM, Sander L, Yrigollen CM, Gelernter J, Grigorenko EL, Lappalainen J, Mane S, Nairn AC, Kleinman JE, Simen AA. Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity. Pharmacogenet Genomics. 2009 Jan; 19(1):53-65.
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Scherer SE, Muzny DM, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Montgomery KT, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Lovering RC, Wheeler DA, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clerc-Blankenburg KP, Davis C, Delgado O, Dinh HH, Draper H, Gonzalez-Garay ML, Havlak P, Jackson LR, Jacob LS, Kelly SH, Li L, Li Z, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Pasternak S, Perez LM, Plopper FJ, Santibanez J, Shen H, Tabor PE, Verduzco D, Waldron L, Wang Q, Williams GA, Zhang J, Zhou J, Allen CC, Amin AG, Anyalebechi V, Bailey M, Barbaria JA, Bimage KE, Bryant NP, Burch PE, Burkett CE, Burrell KL, Calderon E, Cardenas V, Carter K, Casias K, Cavazos I, Cavazos SR, Ceasar H, Chacko J, Chan SN, Chavez D, Christopoulos C, Chu J, Cockrell R, Cox CD, Dang M, Dathorne SR, David R, Davis CM, Davy-Carroll L, Deshazo DR, Donlin JE, D'Souza L, Eaves KA, Egan A, Emery-Cohen AJ, Escotto M, Flagg N, Forbes LD, Gabisi AM, Garza M, Hamilton C, Henderson N, Hernandez O, Hines S, Hogues ME, Huang M, Idlebird DG, Johnson R, Jolivet A, Jones S, Kagan R, King LM, Leal B, Lebow H, Lee S, LeVan JM, Lewis LC, London P, Lorensuhewa LM, Loulseged H, Lovett DA, Lucier A, Lucier RL, Ma J, Madu RC, Mapua P, Martindale AD, Martinez E, Massey E, Mawhiney S, Meador MG, Mendez S, Mercado C, Mercado IC, Merritt CE, Miner ZL, Minja E, Mitchell T, Mohabbat F, Mohabbat K, Montgomery B, Moore N, Morris S, Munidasa M, Ngo RN, Nguyen NB, Nickerson E, Nwaokelemeh OO, Nwokenkwo S, Obregon M, Oguh M, Oragunye N, Oviedo RJ, Parish BJ, Parker DN, Parrish J, Parks KL, Paul HA, Payton BA, Perez A, Perrin W, Pickens A, Primus EL, Pu LL, Puazo M, Quiles MM, Quiroz JB, Rabata D, Reeves K, Ruiz SJ, Shao H, Sisson I, Sonaike T, Sorelle RP, Sutton AE, Svatek AF, Svetz LA, Tamerisa KS, Taylor TR, Teague B, Thomas N, Thorn RD, Trejos ZY, Trevino BK, Ukegbu ON, Urban JB, Vasquez LI, Vera VA, Villasana DM, Wang L, Ward-Moore S, Warren JT, Wei X, White F, Williamson AL, Wleczyk R, Wooden HS, Wooden SH, Yen J, Yoon L, Yoon V, Zorrilla SE, Nelson D, Kucherlapati R, Weinstock G, Gibbs RA. The finished DNA sequence of human chromosome 12. Nature. 2006 Mar 16; 440(7082):346-51.
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Collins R, Achtman M, Ford R, Bullough P, Derrick J. Projection structure of reconstituted Opc outer membrane protein from Neisseria meningitidis. Mol Microbiol. 1999 Apr; 32(1):217-9.
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Ophir R, Graur D. Patterns and rates of indel evolution in processed pseudogenes from humans and murids. Gene. 1997 Dec 31; 205(1-2):191-202.
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Ray MK, Chen CY, Schwartz RJ, DeMayo FJ. Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX). Mol Cell Biol. 1996 May; 16(5):2056-64.
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Tan X, Varughese M, Widger WR. A light-repressed transcript found in Synechococcus PCC 7002 is similar to a chloroplast-specific small subunit ribosomal protein and to a transcription modulator protein associated with sigma 54. J Biol Chem. 1994 Aug 19; 269(33):20905-12.
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Chow KL, Hogan ME, Schwartz RJ. Phased cis-acting promoter elements interact at short distances to direct avian skeletal alpha-actin gene transcription. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1301-5.
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