 Receptors, Adrenergic, beta-2
"Receptors, Adrenergic, beta-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. They are widespread, with clinically important roles in SKELETAL MUSCLE; LIVER; and vascular, bronchial, gastrointestinal, and genitourinary SMOOTH MUSCLE.
| Descriptor ID |
D018343
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| MeSH Number(s) |
D12.776.543.750.069.300.300.340.200 D12.776.543.750.100.150.300.340.725 D12.776.543.750.720.330.300.340.200
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| Concept/Terms |
Receptors, Adrenergic, beta-2- Receptors, Adrenergic, beta-2
- Adrenergic beta-2 Receptors
- Adrenergic beta 2 Receptors
- Receptors, Adrenergic beta-2
- beta-2 Receptors, Adrenergic
- Receptor, Adrenergic, beta-2
- beta 2 Adrenergic Receptors
- beta-2 Adrenergic Receptors
- Adrenergic Receptors, beta-2
- Receptors, beta-2 Adrenergic
- Receptors, beta 2 Adrenergic
- Adrenergic Receptor, beta-2
- Adrenergic Receptor, beta 2
- Receptor, beta-2 Adrenergic
- beta-2 Adrenergic Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.069]
- Receptors, Catecholamine [D12.776.543.750.069.300]
- Receptors, Adrenergic [D12.776.543.750.069.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.069.300.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.069.300.300.340.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.100.150.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.100.150.300.340.725]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.330.300.340]
- Receptors, Adrenergic, beta-2 [D12.776.543.750.720.330.300.340.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-2".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-2" by people in this website by year, and whether "Receptors, Adrenergic, beta-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 2 | 1 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 0 | 3 | | 2000 | 2 | 0 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 7 | 0 | 7 | | 2004 | 2 | 1 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 4 | 0 | 4 | | 2007 | 3 | 0 | 3 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 4 | 0 | 4 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 3 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Adrenergic, beta-2" by people in Profiles.
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Knight JM, Mak G, Shaw J, Porter P, McDermott C, Roberts L, You R, Yuan X, Millien VO, Qian Y, Song LZ, Frazier V, Kim C, Kim JJ, Bond RA, Milner JD, Zhang Y, Mandal PK, Luong A, Kheradmand F, McMurray JS, Corry DB. Long-Acting Beta Agonists Enhance Allergic Airway Disease. PLoS One. 2015; 10(11):e0142212.
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Al-Sawalha N, Pokkunuri I, Omoluabi O, Kim H, Thanawala VJ, Hernandez A, Bond RA, Knoll BJ. Epinephrine Activation of the ß2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS One. 2015; 10(7):e0132559.
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Stoddart LA, Johnstone EKM, Wheal AJ, Goulding J, Robers MB, Machleidt T, Wood KV, Hill SJ, Pfleger KDG. Application of BRET to monitor ligand binding to GPCRs. Nat Methods. 2015 Jul; 12(7):661-663.
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Bigley AB, Rezvani K, Pistillo M, Reed J, Agha N, Kunz H, O'Connor DP, Sekine T, Bollard CM, Simpson RJ. Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Part II: impact of latent cytomegalovirus infection and catecholamine sensitivity. Brain Behav Immun. 2015 Oct; 49:59-65.
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Baker JG, Proudman RG, Hill SJ. Salmeterol's extreme ß2 selectivity is due to residues in both extracellular loops and transmembrane domains. Mol Pharmacol. 2015 Jan; 87(1):103-20.
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Thanawala VJ, Forkuo GS, Stallaert W, Leff P, Bouvier M, Bond R. Ligand bias prevents class equality among beta-blockers. Curr Opin Pharmacol. 2014 Jun; 16:50-7.
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Baker JG, Adams LA, Salchow K, Mistry SN, Middleton RJ, Hill SJ, Kellam B. Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human ß-adrenoceptors. J Med Chem. 2011 Oct 13; 54(19):6874-87.
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Connolly S, Alcaraz L, Bailey A, Cadogan E, Christie J, Cook AR, Fisher AJ, Hill S, Humphries A, Ingall AH, Kane Z, Paine S, Pairaudeau G, Stocks MJ, Young A. Design-driven LO: the discovery of new ultra long acting dibasic ß2-adrenoceptor agonists. Bioorg Med Chem Lett. 2011 Aug 01; 21(15):4612-6.
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Walker JK, Penn RB, Hanania NA, Dickey BF, Bond RA. New perspectives regarding ß(2) -adrenoceptor ligands in the treatment of asthma. Br J Pharmacol. 2011 May; 163(1):18-28.
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Peng H, Bond RA, Knoll BJ. The effects of acute and chronic nadolol treatment on ß2AR signaling in HEK293 cells. Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb; 383(2):209-16.
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