 Tandem Mass Spectrometry
"Tandem Mass Spectrometry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
| Descriptor ID |
D053719
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| MeSH Number(s) |
E05.196.566.880
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| Concept/Terms |
Tandem Mass Spectrometry- Tandem Mass Spectrometry
- Mass Spectrometry, Tandem
- Mass Spectrometry-Mass Spectrometry
- Mass Spectrometry Mass Spectrometry
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Below are MeSH descriptors whose meaning is more general than "Tandem Mass Spectrometry".
Below are MeSH descriptors whose meaning is more specific than "Tandem Mass Spectrometry".
This graph shows the total number of publications written about "Tandem Mass Spectrometry" by people in this website by year, and whether "Tandem Mass Spectrometry" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 5 | 6 | | 2010 | 0 | 5 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 3 | 3 | | 2013 | 1 | 3 | 4 | | 2014 | 1 | 3 | 4 | | 2015 | 1 | 1 | 2 | | 2016 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tandem Mass Spectrometry" by people in Profiles.
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Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. IgG Fc domains that bind C1q but not effector Fc? receptors delineate the importance of complement-mediated effector functions. Nat Immunol. 2017 Aug; 18(8):889-898.
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Farhan N, Fitzpatrick S, Shim YM, Paige M, Chow DS. Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation. J Pharm Biomed Anal. 2016 Sep 05; 128:46-52.
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Zhang D, Chow DS, Renbarger JL. Simultaneous quantification of mycophenolic acid and its glucuronide metabolites in human plasma by an UPLC-MS/MS assay. Biomed Chromatogr. 2016 Oct; 30(10):1648-55.
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Gadgil P, Ibrahim F, Chow DS. UPLC-MS/MS assay of 21-aminosteroid (lazaroid U74389G) for application in pharmacokinetic study. J Pharm Biomed Anal. 2016 Apr 15; 122:90-7.
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Zhang D, Wu L, Chow DS, Tam VH, Rios DR. Quantitative determination of dopamine in human plasma by a highly sensitive LC-MS/MS assay: Application in preterm neonates. J Pharm Biomed Anal. 2016 Jan 05; 117:227-31.
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Greening DW, Xu R, Ji H, Tauro BJ, Simpson RJ. A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods. Methods Mol Biol. 2015; 1295:179-209.
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Zhang D, Rios DR, Tam VH, Chow DS. Development and validation of a highly sensitive LC-MS/MS assay for the quantification of arginine vasopressin in human plasma and urine: Application in preterm neonates and child. J Pharm Biomed Anal. 2014 Oct; 99:67-73.
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Zhou J, Sulaiman Z, Llorin RM, Hee KH, Lee LS, Lye DC, Fisher DA, Tam VH. Pharmacokinetics of ertapenem in outpatients with complicated urinary tract infections. J Antimicrob Chemother. 2014 Sep; 69(9):2517-21.
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Cui Z, Chow DS, Wu L, Lazar DA, Rodrigo R, Olutoye OO, Olutoye OA. High performance liquid chromatography-tandem mass spectrometric assay of dexmedetomidine in plasma, urine and amniotic fluid samples for pregnant ewe model. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 15; 961:13-9.
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He W, Kuang Y, Xing X, Simpson RJ, Huang H, Yang T, Chen J, Yang L, Liu E, He W, Gu J. Proteomic comparison of 3D and 2D glioma models reveals increased HLA-E expression in 3D models is associated with resistance to NK cell-mediated cytotoxicity. J Proteome Res. 2014 May 02; 13(5):2272-81.
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