 Enzyme Activation
"Enzyme Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
| Descriptor ID |
D004789
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| MeSH Number(s) |
G02.111.087.245 G02.149.115.245 G03.495.368
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| Concept/Terms |
Enzyme Activation- Enzyme Activation
- Activation, Enzyme
- Activations, Enzyme
- Enzyme Activations
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Below are MeSH descriptors whose meaning is more general than "Enzyme Activation".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Activation".
This graph shows the total number of publications written about "Enzyme Activation" by people in this website by year, and whether "Enzyme Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 3 | 3 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 4 | 4 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 6 | 6 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 5 | 5 | | 2008 | 0 | 6 | 6 | | 2010 | 0 | 4 | 4 | | 2011 | 0 | 6 | 6 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 6 | 6 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enzyme Activation" by people in Profiles.
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Bollu LR, Katreddy RR, Blessing AM, Pham N, Zheng B, Wu X, Weihua Z. Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation. Oncotarget. 2015 Oct 27; 6(33):34992-5003.
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Dyari HR, Rawling T, Bourget K, Murray M. Synthetic ?-3 epoxyfatty acids as antiproliferative and pro-apoptotic agents in human breast cancer cells. J Med Chem. 2014 Sep 11; 57(17):7459-64.
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Kong Q, Chang LC, Takahashi K, Liu Q, Schulte DA, Lai L, Ibabao B, Lin Y, Stouffer N, Das Mukhopadhyay C, Xing X, Seyb KI, Cuny GD, Glicksman MA, Lin CL. Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection. J Clin Invest. 2014 Mar; 124(3):1255-67.
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Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. J Biol Chem. 2013 Dec 20; 288(51):36598-609.
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Zhou Y, Bollu LR, Tozzi F, Ye X, Bhattacharya R, Gao G, Dupre E, Xia L, Lu J, Fan F, Bellister S, Ellis LM, Weihua Z. ATP citrate lyase mediates resistance of colorectal cancer cells to SN38. Mol Cancer Ther. 2013 Dec; 12(12):2782-91.
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Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec; 12(12):2651-62.
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Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X. Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. Dev Biol. 2013 Nov 15; 383(2):239-52.
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Ishikawa T, Yuhanna IS, Umetani J, Lee WR, Korach KS, Shaul PW, Umetani M. LXRß/estrogen receptor-a signaling in lipid rafts preserves endothelial integrity. J Clin Invest. 2013 Aug; 123(8):3488-97.
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McNamara CR, Ahuja R, Osafo-Addo AD, Barrows D, Kettenbach A, Skidan I, Teng X, Cuny GD, Gerber S, Degterev A. Akt Regulates TNFa synthesis downstream of RIP1 kinase activation during necroptosis. PLoS One. 2013; 8(3):e56576.
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Pinan-Lucarre B, Gabel CV, Reina CP, Hulme SE, Shevkoplyas SS, Slone RD, Xue J, Qiao Y, Weisberg S, Roodhouse K, Sun L, Whitesides GM, Samuel A, Driscoll M. The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans. PLoS Biol. 2012; 10(5):e1001331.
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