 Proteolysis
"Proteolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cleavage of proteins into smaller peptides or amino acids either by PROTEASES or non-enzymatically (e.g., Hydrolysis). It does not include Protein Processing, Post-Translational.
| Descriptor ID |
D059748
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| MeSH Number(s) |
G02.111.087.710 G02.149.115.710 G03.495.802
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| Concept/Terms |
Proteolysis- Proteolysis
- Proteolyses
- Protein Degradation
- Degradation, Protein
- Degradations, Protein
- Protein Degradations
Protein Digestion- Protein Digestion
- Digestion, Protein
- Digestions, Protein
- Protein Digestions
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Below are MeSH descriptors whose meaning is more general than "Proteolysis".
Below are MeSH descriptors whose meaning is more specific than "Proteolysis".
This graph shows the total number of publications written about "Proteolysis" by people in this website by year, and whether "Proteolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 2 | 2 | | 2013 | 1 | 4 | 5 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Proteolysis" by people in Profiles.
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Mitchell M, Mali S, King CC, Bark SJ. Enhancing MALDI time-of-flight mass spectrometer performance through spectrum averaging. PLoS One. 2015; 10(3):e0120932.
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Lee S, Kang D, Ra EA, Lee TA, Ploegh HL, Park B. Negative self-regulation of TLR9 signaling by its N-terminal proteolytic cleavage product. J Immunol. 2014 Oct 01; 193(7):3726-35.
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van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ. TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11425-30.
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Xiong J, Xia M, Xu M, Zhang Y, Abais JM, Li G, Riebling CR, Ritter JK, Boini KM, Li PL. Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes. J Cell Mol Med. 2013 Dec; 17(12):1598-607.
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Farmer LM, Rinaldi MA, Young PG, Danan CH, Burkhart SE, Bartel B. Disrupting autophagy restores peroxisome function to an Arabidopsis lon2 mutant and reveals a role for the LON2 protease in peroxisomal matrix protein degradation. Plant Cell. 2013 Oct; 25(10):4085-100.
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Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec; 12(12):2651-62.
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Greening DW, Ji H, Kapp EA, Simpson RJ. Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis. Biochim Biophys Acta. 2013 Nov; 1834(11):2293-307.
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Greening DW, Kapp EA, Ji H, Speed TP, Simpson RJ. Colon tumour secretopeptidome: insights into endogenous proteolytic cleavage events in the colon tumour microenvironment. Biochim Biophys Acta. 2013 Nov; 1834(11):2396-407.
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Hart MJ, Glicksman M, Liu M, Sharma MK, Cuny G, Galvan V. Development of a high-throughput screen targeting caspase-8-mediated cleavage of the amyloid precursor protein. Anal Biochem. 2012 Feb 15; 421(2):467-76.
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Hook V, Funkelstein L, Wegrzyn J, Bark S, Kindy M, Hook G. Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease. Biochim Biophys Acta. 2012 Jan; 1824(1):89-104.
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