 Monoamine Oxidase
"Monoamine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
| Descriptor ID |
D008995
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| MeSH Number(s) |
D08.811.682.664.750
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| Concept/Terms |
Monoamine Oxidase- Monoamine Oxidase
- Oxidase, Monoamine
- Amine Oxidase (Flavin-Containing)
- MAO
- Tyramine Oxidase
- Oxidase, Tyramine
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Below are MeSH descriptors whose meaning is more general than "Monoamine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Monoamine Oxidase".
This graph shows the total number of publications written about "Monoamine Oxidase" by people in this website by year, and whether "Monoamine Oxidase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monoamine Oxidase" by people in Profiles.
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Grigorenko EL, De Young CG, Eastman M, Getchell M, Haeffel GJ, Klinteberg Ba, Koposov RA, Oreland L, Pakstis AJ, Ponomarev OA, Ruchkin VV, Singh JP, Yrigollen CM. Aggressive behavior, related conduct problems, and variation in genes affecting dopamine turnover. Aggress Behav. 2010 May-Jun; 36(3):158-76.
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Qiu HT, Meng HQ, Song C, Xiu MH, Chen DC, Zhu FY, Wu GY, Kosten TA, Kosten TR, Zhang XY. Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population. Brain Res. 2009 Sep 01; 1287:67-73.
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Ruchkin VV, Koposov RA, af Klinteberg B, Oreland L, Grigorenko EL. Platelet MAO-B, personality, and psychopathology. J Abnorm Psychol. 2005 Aug; 114(3):477-82.
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Lucas-Teixeira VA, Hussain T, Serrão P, Soares-da-Silva P, Lokhandwala MF. Intestinal dopaminergic activity in obese and lean Zucker rats: response to high salt intake. Clin Exp Hypertens. 2002 Jul; 24(5):383-96.
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Garpenstrand H, Longato-Stadler E, af Klinteberg B, Grigorenko E, Damberg M, Oreland L, Hallman J. Low platelet monoamine oxidase activity in Swedish imprisoned criminal offenders. Eur Neuropsychopharmacol. 2002 Apr; 12(2):135-40.
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Vieira-Coelho MA, Hussain T, Kansra V, Serrao MP, Guimaraes JT, Pestana M, Soares-Da-Silva P, Lokhandwala MF. Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats. Hypertension. 1999 Oct; 34(4 Pt 1):666-72.
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Clarke DE, Jandhyala B. Acute and chronic effects of tetrahydrocannabinols on monoamide oxidase activity: possible vehicle/tetrahydrocannabinol interactions. Res Commun Chem Pathol Pharmacol. 1977 Jul; 17(3):471-80.
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Clarke DE, Jandhyala BS, Cavero I, Dixit BN, Buckley JP. A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels. Can J Physiol Pharmacol. 1974 Jun; 52(3):641-8.
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