 Receptors, Purinergic P1
"Receptors, Purinergic P1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface receptors that prefer ADENOSINE to other endogenous PURINES. Purinergic P1 receptors are widespread in the body including the cardiovascular, respiratory, immune, and nervous systems. There are at least two pharmacologically distinguishable types (A1 and A2, or Ri and Ra).
| Descriptor ID |
D018047
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| MeSH Number(s) |
D12.776.543.750.100.700.700 D12.776.543.750.720.700.700
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| Concept/Terms |
Receptors, Purinergic P1- Receptors, Purinergic P1
- Adenosine Receptors
- Receptors, Adenosine
- P1 Purinoceptors
- Purinoceptors, P1
- Purinergic P1 Receptors
- P1 Receptors, Purinergic
- Receptor, Purinergic P1
- P1 Receptor, Purinergic
- Purinergic P1 Receptor
- Adenosine Receptor
- Receptor, Adenosine
- P1 Purinoceptor
- Purinoceptor, P1
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Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P1".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P1".
This graph shows the total number of publications written about "Receptors, Purinergic P1" by people in this website by year, and whether "Receptors, Purinergic P1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 0 | 3 | | 1994 | 5 | 0 | 5 | | 1995 | 3 | 1 | 4 | | 1996 | 3 | 0 | 3 | | 1997 | 2 | 0 | 2 | | 1998 | 6 | 0 | 6 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Purinergic P1" by people in Profiles.
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Hallworth R, Cato M, Colbert C, Rea MA. Presynaptic adenosine A1 receptors regulate retinohypothalamic neurotransmission in the hamster suprachiasmatic nucleus. J Neurobiol. 2002 Sep 05; 52(3):230-40.
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Cordeaux Y, Briddon SJ, Megson AE, McDonnell J, Dickenson JM, Hill SJ. Influence of receptor number on functional responses elicited by agonists acting at the human adenosine A(1) receptor: evidence for signaling pathway-dependent changes in agonist potency and relative intrinsic activity. Mol Pharmacol. 2000 Nov; 58(5):1075-84.
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Walker EM, Bispham JR, Hill SJ. Nonselective effects of the putative phospholipase C inhibitor, U73122, on adenosine A1 receptor-mediated signal transduction events in Chinese hamster ovary cells. Biochem Pharmacol. 1998 Dec 01; 56(11):1455-62.
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Dickenson JM, Hill SJ. Potentiation of adenosine A1 receptor-mediated inositol phospholipid hydrolysis by tyrosine kinase inhibitors in CHO cells. Br J Pharmacol. 1998 Nov; 125(5):1049-57.
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Haynes JM, Alexander SP, Hill SJ. A1 and A2 adenosine receptor modulation of contractility in the cauda epididymis of the guinea-pig. Br J Pharmacol. 1998 Oct; 125(3):570-6.
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Dickenson JM, Hill SJ. Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells. Eur J Pharmacol. 1998 Aug 14; 355(1):85-93.
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Dickenson JM, Blank JL, Hill SJ. Human adenosine A1 receptor and P2Y2-purinoceptor-mediated activation of the mitogen-activated protein kinase cascade in transfected CHO cells. Br J Pharmacol. 1998 Aug; 124(7):1491-9.
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Haynes JM, Alexander SP, Hill SJ. A1 adenosine receptor modulation of electrically-evoked contractions in the bisected vas deferens and cauda epididymis of the guinea-pig. Br J Pharmacol. 1998 Jul; 124(5):964-70.
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Cooper J, Hill SJ, Alexander SP. An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells. Br J Pharmacol. 1997 Oct; 122(3):546-50.
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Dickenson JM, Hill SJ. Transfected adenosine A1 receptor-mediated modulation of thrombin-stimulated phospholipase C and phospholipase A2 activity in CHO cells. Eur J Pharmacol. 1997 Feb 19; 321(1):77-86.
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