 GTP-Binding Proteins
"GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.
| Descriptor ID |
D019204
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| MeSH Number(s) |
D08.811.277.040.330.300 D12.776.157.325
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| Concept/Terms |
GTP-Binding Proteins- GTP-Binding Proteins
- GTP Binding Proteins
- Proteins, GTP-Binding
- G-Proteins
- G Proteins
- GTP-Binding Protein
- GTP Binding Protein
- Protein, GTP-Binding
- Guanine Nucleotide Regulatory Proteins
- GTP-Regulatory Protein
- GTP Regulatory Protein
- Protein, GTP-Regulatory
- GTP-Regulatory Proteins
- GTP Regulatory Proteins
- Proteins, GTP-Regulatory
- Guanine Nucleotide Coupling Protein
- G-Protein
- G Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Proteins".
This graph shows the total number of publications written about "GTP-Binding Proteins" by people in this website by year, and whether "GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1993 | 3 | 1 | 4 | | 1994 | 0 | 2 | 2 | | 1995 | 6 | 2 | 8 | | 1996 | 0 | 1 | 1 | | 1997 | 6 | 0 | 6 | | 1998 | 3 | 5 | 8 | | 1999 | 3 | 4 | 7 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Proteins" by people in Profiles.
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Stoddart LA, Kellam B, Briddon SJ, Hill SJ. Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol. 2014 Aug; 171(16):3827-44.
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Senthong P, Millington CL, Wilkinson OJ, Marriott AS, Watson AJ, Reamtong O, Eyers CE, Williams DM, Margison GP, Povey AC. The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase. Nucleic Acids Res. 2013 Mar 01; 41(5):3047-55.
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Alcock J, Warren AY, Goodson YJ, Hill SJ, Khan RN, Lymn JS. Inhibition of tissue transglutaminase 2 attenuates contractility of pregnant human myometrium. Biol Reprod. 2011 Apr; 84(4):646-53.
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Bridge LJ, King JR, Hill SJ, Owen MR. Mathematical modelling of signalling in a two-ligand G-protein coupled receptor system: agonist-antagonist competition. Math Biosci. 2010 Feb; 223(2):115-32.
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George L, Lokhandwala MF, Asghar M. Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1174-80.
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Banday AA, Lau YS, Lokhandwala MF. Oxidative stress causes renal dopamine D1 receptor dysfunction and salt-sensitive hypertension in Sprague-Dawley rats. Hypertension. 2008 Feb; 51(2):367-75.
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Ahmad Banday A, Lokhandwala MF. Defective renal dopamine D1 receptor function contributes to hyperinsulinemia-mediated hypertension. Clin Exp Hypertens. 2006 Nov; 28(8):695-705.
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Marwaha A, Lokhandwala MF. Tempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic rats. Am J Physiol Renal Physiol. 2006 Jul; 291(1):F58-66.
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Banday AA, Marwaha A, Tallam LS, Lokhandwala MF. Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes. 2005 Jul; 54(7):2219-26.
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Trivedi M, Narkar VA, Hussain T, Lokhandwala MF. Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F921-31.
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