 Epinephrine
"Epinephrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
| Descriptor ID |
D004837
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| MeSH Number(s) |
D02.033.100.291.310 D02.092.063.291.310 D02.092.211.215.311.461 D02.092.311.461
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| Concept/Terms |
Epinephrine- Epinephrine
- Adrenaline
- 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
Epifrin- Epifrin
- Allergan Brand of Adrenaline Hydrochloride
Epinephrine Bitartrate- Epinephrine Bitartrate
- Adrenaline Bitartrate
- Epinephrine Hydrogen Tartrate
- Adrenaline Acid Tartrate
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Below are MeSH descriptors whose meaning is more general than "Epinephrine".
Below are MeSH descriptors whose meaning is more specific than "Epinephrine".
This graph shows the total number of publications written about "Epinephrine" by people in this website by year, and whether "Epinephrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1986 | 2 | 1 | 3 | | 1987 | 0 | 1 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 1 | 1 | 2 | | 1990 | 0 | 1 | 1 | | 1992 | 1 | 1 | 2 | | 1993 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 3 | 3 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 3 | 3 | | 2007 | 1 | 1 | 2 | | 2009 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 2 | 3 |
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Below are the most recent publications written about "Epinephrine" by people in Profiles.
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Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P, Bond RA. ß-Blockers have differential effects on the murine asthma phenotype. Br J Pharmacol. 2015 Oct; 172(20):4833-46.
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Al-Sawalha N, Pokkunuri I, Omoluabi O, Kim H, Thanawala VJ, Hernandez A, Bond RA, Knoll BJ. Epinephrine Activation of the ß2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS One. 2015; 10(7):e0132559.
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Bigley AB, Rezvani K, Pistillo M, Reed J, Agha N, Kunz H, O'Connor DP, Sekine T, Bollard CM, Simpson RJ. Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Part II: impact of latent cytomegalovirus infection and catecholamine sensitivity. Brain Behav Immun. 2015 Oct; 49:59-65.
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Brody GH, Yu T, MacKillop J, Miller GE, Chen E, Obasi EM, Beach SR. Catecholamine levels and delay discounting forecast drug use among African American youths. Addiction. 2014 Jul; 109(7):1112-8.
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Weeks PA, Teng Y, Wu L, Sun M, Yang Z, Chow DS. Chemical and physical compatibility of an intravenous solution of epinephrine with calcium chloride. Int J Pharm Compd. 2014 Mar-Apr; 18(2):152-8.
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Thanawala VJ, Forkuo GS, Al-Sawalha N, Azzegagh Z, Nguyen LP, Eriksen JL, Tuvim MJ, Lowder TW, Dickey BF, Knoll BJ, Walker JK, Bond RA. ß2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):220-9.
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Ostrin LA, Glasser A. Autonomic drugs and the accommodative system in rhesus monkeys. Exp Eye Res. 2010 Jan; 90(1):104-12.
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Salim S, Desai AN, Taneja M, Eikenburg DC. Chronic adrenaline treatment fails to down-regulate the Del301-303-alpha2B-adrenoceptor in neuronal cells. Br J Pharmacol. 2009 Sep; 158(1):314-27.
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Bawa-Khalfe T, Altememi GF, Mandyam CD, Schwarz LA, Eikenburg DC, Standifer KM. The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment. BMC Pharmacol. 2007 Dec 20; 7:16.
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Salim S, Standifer KM, Eikenburg DC. Extracellular signal-regulated kinase 1/2-mediated transcriptional regulation of G-protein-coupled receptor kinase 3 expression in neuronal cells. J Pharmacol Exp Ther. 2007 Apr; 321(1):51-9.
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