 Isoproterenol
"Isoproterenol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
| Descriptor ID |
D007545
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| MeSH Number(s) |
D02.033.100.291.439 D02.092.063.291.439 D02.092.311.649
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| Concept/Terms |
Isoproterenol- Isoproterenol
- Isoprenaline
- Isopropylnorepinephrine
- Isopropylarterenol
- Isopropylnoradrenaline
- 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol
- Isopropyl Noradrenaline
- Noradrenaline, Isopropyl
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Below are MeSH descriptors whose meaning is more general than "Isoproterenol".
Below are MeSH descriptors whose meaning is more specific than "Isoproterenol".
This graph shows the total number of publications written about "Isoproterenol" by people in this website by year, and whether "Isoproterenol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1987 | 1 | 1 | 2 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 3 | 3 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 4 | 4 | | 1994 | 0 | 2 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Isoproterenol" by people in Profiles.
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Guillory AN, Yin X, Wijaya CS, Diaz Diaz AC, Rababa'h A, Singh S, Atrooz F, Sadayappan S, McConnell BK. Enhanced cardiac function in Gravin mutant mice involves alterations in the ß-adrenergic receptor signaling cascade. PLoS One. 2013; 8(9):e74784.
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Xiong J, Xia M, Yi F, Abais JM, Li N, Boini KM, Li PL. Regulation of renin release via cyclic ADP-ribose-mediated signaling: evidence from mice lacking CD38 gene. Cell Physiol Biochem. 2013; 31(1):44-55.
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Kim SJ, Zhang H, Khaliulin I, Choisy SC, Bond R, Lin H, El Haou S, Milnes JT, Hancox JC, Suleiman MS, James AF. Activation of glibenclamide-sensitive ATP-sensitive K+ channels during ß-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia. Circ Arrhythm Electrophysiol. 2012 Dec; 5(6):1184-92.
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Baker JG, Kemp P, March J, Fretwell L, Hill SJ, Gardiner SM. Predicting in vivo cardiovascular properties of ß-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. FASEB J. 2011 Dec; 25(12):4486-97.
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McConnell BK, Popovic Z, Mal N, Lee K, Bautista J, Forudi F, Schwartzman R, Jin JP, Penn M, Bond M. Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis. J Biol Chem. 2009 Jan 16; 284(3):1583-92.
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Tran TM, Friedman J, Baameur F, Knoll BJ, Moore RH, Clark RB. Characterization of beta2-adrenergic receptor dephosphorylation: Comparison with the rate of resensitization. Mol Pharmacol. 2007 Jan; 71(1):47-60.
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Matkovich SJ, Diwan A, Klanke JL, Hammer DJ, Marreez Y, Odley AM, Brunskill EW, Koch WJ, Schwartz RJ, Dorn GW. Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling. Circ Res. 2006 Oct 27; 99(9):996-1003.
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Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. J Biol Chem. 2006 Mar 17; 281(11):7684-92.
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Carter AA, Hill SJ. Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells. J Pharmacol Exp Ther. 2005 Nov; 315(2):839-48.
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Ogletree-Hughes ML, Stull LB, Sweet WE, Smedira NG, McCarthy PM, Moravec CS. Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart. Circulation. 2001 Aug 21; 104(8):881-6.
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