 Albuterol
"Albuterol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
| Descriptor ID |
D000420
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| MeSH Number(s) |
D02.033.100.291.057 D02.092.063.291.057 D02.092.471.683.061
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| Concept/Terms |
Albuterol- Albuterol
- Salbutamol
- 2-t-Butylamino-1-(4-hydroxy-3-hydroxy-3-hydroxymethyl)phenylethanol
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Below are MeSH descriptors whose meaning is more general than "Albuterol".
Below are MeSH descriptors whose meaning is more specific than "Albuterol".
This graph shows the total number of publications written about "Albuterol" by people in this website by year, and whether "Albuterol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 2 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 1 | 1 | 2 | | 1990 | 0 | 2 | 2 | | 1993 | 1 | 1 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Albuterol" by people in Profiles.
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Knight JM, Mak G, Shaw J, Porter P, McDermott C, Roberts L, You R, Yuan X, Millien VO, Qian Y, Song LZ, Frazier V, Kim C, Kim JJ, Bond RA, Milner JD, Zhang Y, Mandal PK, Luong A, Kheradmand F, McMurray JS, Corry DB. Long-Acting Beta Agonists Enhance Allergic Airway Disease. PLoS One. 2015; 10(11):e0142212.
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Baker JG, Proudman RG, Hill SJ. Salmeterol's extreme ß2 selectivity is due to residues in both extracellular loops and transmembrane domains. Mol Pharmacol. 2015 Jan; 87(1):103-20.
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Hanania NA, Mannava B, Franklin AE, Lipworth BJ, Williamson PA, Garner WJ, Dickey BF, Bond RA. Response to salbutamol in patients with mild asthma treated with nadolol. Eur Respir J. 2010 Oct; 36(4):963-5.
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Moore RH, Millman EE, Godines V, Hanania NA, Tran TM, Peng H, Dickey BF, Knoll BJ, Clark RB. Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization. Am J Respir Cell Mol Biol. 2007 Feb; 36(2):254-61.
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Carter AA, Hill SJ. Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells. J Pharmacol Exp Ther. 2005 Nov; 315(2):839-48.
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McDonnell J, Latif ML, Rees ES, Bevan NJ, Hill SJ. Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human beta2-adrenoceptor. Br J Pharmacol. 1998 Oct; 125(4):717-26.
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January B, Seibold A, Allal C, Whaley BS, Knoll BJ, Moore RH, Dickey BF, Barber R, Clark RB. Salmeterol-induced desensitization, internalization and phosphorylation of the human beta2-adrenoceptor. Br J Pharmacol. 1998 Feb; 123(4):701-11.
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Morrison KJ, Moore RH, Carsrud ND, Trial J, Millman EE, Tuvim M, Clark RB, Barber R, Dickey BF, Knoll BJ. Repetitive endocytosis and recycling of the beta 2-adrenergic receptor during agonist-induced steady state redistribution. Mol Pharmacol. 1996 Sep; 50(3):692-9.
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McCrea KE, Hill SJ. Comparison of duration of agonist action at beta 1- and beta 2- adrenoceptors in C6 glioma cells: evidence that the long duration of action of salmeterol is specific to the beta 2-adrenoceptor. Mol Pharmacol. 1996 May; 49(5):927-37.
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Apparsundaram S, Eikenburg DC. Role of prejunctional beta adrenoceptors in rat cardiac sympathetic neurotransmission. J Pharmacol Exp Ther. 1995 Feb; 272(2):519-26.
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