Radioligand Assay
"Radioligand Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Quantitative determination of receptor (binding) proteins in body fluids or tissue using radioactively labeled binding reagents (e.g., antibodies, intracellular receptors, plasma binders).
Descriptor ID |
D011869
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MeSH Number(s) |
E01.370.225.985 E01.370.374.650 E01.370.384.720 E05.200.985
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Concept/Terms |
Radioligand Assay- Radioligand Assay
- Assay, Radioligand
- Assays, Radioligand
- Radioligand Assays
- Radioreceptor Assay
- Assay, Radioreceptor
- Assays, Radioreceptor
- Radioreceptor Assays
- Protein-Binding Radioassay
- Protein Binding Radioassay
- Protein-Binding Radioassays
- Radioassay, Protein-Binding
- Radioassays, Protein-Binding
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Below are MeSH descriptors whose meaning is more general than "Radioligand Assay".
Below are MeSH descriptors whose meaning is more specific than "Radioligand Assay".
This graph shows the total number of publications written about "Radioligand Assay" by people in this website by year, and whether "Radioligand Assay" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1986 | 0 | 1 | 1 | 1992 | 0 | 2 | 2 | 1994 | 0 | 3 | 3 | 1995 | 0 | 1 | 1 | 1996 | 0 | 2 | 2 | 1999 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2001 | 0 | 2 | 2 | 2003 | 0 | 1 | 1 | 2004 | 0 | 3 | 3 | 2006 | 0 | 3 | 3 | 2007 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Radioligand Assay" by people in Profiles.
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Hothersall JD, Guo D, Sarda S, Sheppard RJ, Chen H, Keur W, Waring MJ, IJzerman AP, Hill SJ, Dale IL, Rawlins PB. Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics. Mol Pharmacol. 2017 Jan; 91(1):25-38.
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Stoddart LA, Kilpatrick LE, Briddon SJ, Hill SJ. Probing the pharmacology of G protein-coupled receptors with fluorescent ligands. Neuropharmacology. 2015 Nov; 98:48-57.
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Baker JG, Adams LA, Salchow K, Mistry SN, Middleton RJ, Hill SJ, Kellam B. Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human ß-adrenoceptors. J Med Chem. 2011 Oct 13; 54(19):6874-87.
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Hu B, Unwalla RJ, Goljer I, Jetter JW, Quinet EM, Berrodin TJ, Basso MD, Feingold IB, Nilsson AG, Wilhelmsson A, Evans MJ, Wrobel JE. Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist. J Med Chem. 2010 Apr 22; 53(8):3296-304.
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Baker JG, Middleton R, Adams L, May LT, Briddon SJ, Kellam B, Hill SJ. Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands. Br J Pharmacol. 2010 Feb; 159(4):772-86.
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Baker JG, Proudman RG, Hawley NC, Fischer PM, Hill SJ. Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor. Mol Pharmacol. 2008 Nov; 74(5):1246-60.
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Middleton RJ, Briddon SJ, Cordeaux Y, Yates AS, Dale CL, George MW, Baker JG, Hill SJ, Kellam B. New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells. J Med Chem. 2007 Feb 22; 50(4):782-93.
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Xu Y, Etgen GJ, Broderick CL, Canada E, Gonzalez I, Lamar J, Montrose-Rafizadeh C, Oldham BA, Osborne JJ, Xie C, Shi Q, Winneroski LL, York J, Yumibe N, Zink R, Mantlo N. Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile. J Med Chem. 2006 Sep 21; 49(19):5649-52.
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Desai AN, Salim S, Standifer KM, Eikenburg DC. Involvement of G protein-coupled receptor kinase (GRK) 3 and GRK2 in down-regulation of the alpha2B-adrenoceptor. J Pharmacol Exp Ther. 2006 Jun; 317(3):1027-35.
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Hill SJ. G-protein-coupled receptors: past, present and future. Br J Pharmacol. 2006 Jan; 147 Suppl 1:S27-37.
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